Innovative Concept Grant Winner: Patricia Mongini, PhD
The Feinstein Institute for Medical Research,
North Shore — LIJ Health System,
Manhasset, New York
B cell-expressed COX-2 and Sjögren's syndrome development
Abstract

Olga J. Baker, DDS, PhD*
University of Missouri
Effects of pro-inflammatory cytokines on polarized salivary epithelium
Abstract
* - This grant was first awarded in 2006-07 and has been renewed for a second year in 2007-08.

Patrizio Caturegli, MD
Johns Hopkins University,
Baltimore, Maryland
Role of IL-12 in the inducible BALT found in Sjögren's lungs
Abstract

Lynn C. Epstein, MD (PI) and
Athena Papas, DMD, PhD (Co-PI)
Tufts University, School of Dental Medicine,
Boston, Massachusetts
Characterizations of cognitive dysfunction in Sjögren's syndrome patients
Abstract

Denise Faustman, MD, PhD
Massachusetts General Hospital,
Harvard University,
Charlestown, Massachusetts
Examination of human spleens for a Hox11 expressing stem cell involved in salivary epithelial regeneration
Abstract

Olga J. Baker, DDS, PhD
University of Missouri
Effects of pro-inflammatory cytokines on polarized salivary epithelium
Abstract

Yongmei Li, PhD*
University of Pennsylvania
Cellular dynamics in mouse models of Sjögren's syndrome
Abstract
* - This grant was first awarded in 2005 and has been renewed for a second year in 2006.

Cristian A. Perez, PhD
The Rockefeller University
Characterizations of brain areas innervating salivary and lacrimal glands
Abstract

Robert M. Clancy, PhD
NYU Hospital for Joints Diseases
Molecular mechanisms of cardiac injury by anti-SSA/Ro — SSB/La antibodies
Abstract

Yongmei Li, PhD
University of Pennsylvania, Philadelphia, PA
Cellular dynamics in mouse models of Sjögren's syndrome

Cristian A. Perez, PhD
The Rockefeller University, New York, NY
Characterization of brain areas innervating salivary and lacrimal glands

Saadia Rashid, MD
Schepens Eye Research Institute, Harvard Medical School, Cambridge, MA
Corneal immunity in ocular surface disease in Sjögren’s syndrome and its treatment by topical application of omega-3 and omega-6 fatty acids.

Shohta Kodama, MD, PhD
Harvard Medical School, Boston, MA
"Evaluation of salivary and lacrimal gland regeneration during the reversal of autoimmunity in NOD mice"

Chuanqing Ding, MD, PhD
University of Southern California, Los Angeles, CA
"Lacrimal gland and nitric oxide in a rabbit model of Sjögren's syndrome"
Second year grant

Chuanqing Ding, MD, PhD
University of Southern California, Los Angeles, CA
"Lacrimal gland and nitric oxide in a rabbit model of Sjögren's syndrome"

Seunghee Cha, DDS, PhD
University of Florida, Gainesville, FL
"Anti-type 3 muscarinic acetylcholine receptor autoantibody-mediated alterations of cytosolic calcium concentration and Aquaporin 5 translocation in Sjögren's syndrome patients"

Vidya Sankar, DMD
National Institute for Dental and Craniofacial Research, NIH
SSF-NIDCR Clinical Fellowship

Abha Sood, MD
Schepens Eye Research Institute, Boston, MA
"The Relationship between Mucin Expression, Glycosylation and Ocular Surface Inflammation in Sjögren's Syndrome"

Jason Brayer, PhD
La Jolla Institute of Allergy and Immunology, San Diego, CA
"Immunomodulation of T lymphocytes by anti-muscarinic antibodies associated with Sjögren's syndrome"

Kirsten Limesand, PhD
University of Colorado, Health Sciences Center
"Suppression of Salivary Gland Apoptosis by Akt"

Hiroko Yamagami, MD, PhD
Schepens Eye Research Institute, Boston, MA
"Sjögren's Syndrome: Androgen deficiency and evaporative dry eye"

Eva Rorer, MD
Johns Hopkins University, Baltimore, MD
"Cytokine production in autoimmune dacryoadenitis"

Toshiaki Maruyama, MD, PhD
Scripps Research Clinic, La Jolla, CA
"Generation of recombinant anti-120K anti-fodrin antibodies from Sjögren's syndrome patients"

Jyrki Tornwall, DDS, MD, PhD
Scripps Research Clinic, La Jolla, CA
"Pathomechanisms of the glandular atrophy in Sjögren's syndrome"

Gallya Gannott, DDS
National Institutes of Health, Bethesda, MD
"Development of a non-invasive method for the diagnosis of Sjögren's syndrome in the minor salivary gland"

Ikuko Toda, MD
Schepens Eye Research Institute, Boston, MA
"Role of epithelial cell cytokines in the androgen-induced suppression of autoimmune disease in lacrimal glands of a mouse model of Sjögren's syndrome"

Jianhua Cheng, MD
University of Alabama at Birmingham
"Modulation of human Fas apoptosis gene expression in Sjögren's syndrome"

Noriyoshi Ogawa, MD
University of Texas Health Science Center at San Antonio
"Cytokine profiles in Sjögren's syndrome and guides to new therapy"

Donald B. Bloch, MD
Massachusetts General Hospital, Boston, MA
"Characterization of a novel Sjögren's syndrome autoantigen"

Peter Girow, MD
Doheney Institute, University of Southern California, Los Angeles, CA
"The pathophysiology of lacrimal gland disease"

Zhiyan Huang, MD
Schepens Eye Research Institute, Boston, MA
"The role of viruses and hormones in Sjögren's syndrome and lacrimal gland disease"

Peter Girow, MD
Doheney Institute, University of Southern California, Los Angeles, CA
"The pathophysiology of lacrimal gland disease"