The Foundation recognizes excellence in research by new and/or young investigators who present outstanding abstracts on Sjögren’s research at professional meetings.

The SSF Outstanding Abstract Award is designed to reward exceptional research efforts and encourage investigators to continue their focus on Sjögren’s throughout their career.  

2016 Award Recipient

American College of Rheumatology Scientific Meeting

Nadia Howard-Tripp, MA, MBSS
Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom

Abstract: Rethinking Primary Sjögren’s Syndrome: Stratification by Clinical Phenotypes to Improve Understanding of Disease Pathogenesis, Trial Design, Clinical Management and Prospective Health Gains? Download Abstract  

Honorable Mention:

Syed Muhammad Shakaib Quadri, MD
Oklahoma Health Science Center and Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma

Abstract: The Unusual Cross-Reactivity of Anti Muscarinic Receptor 3 Monoclonal Antibodies Derived from Salivary Glands of Sjögren’s Syndrome Patients to Ro PeptidesDownload Abstract

2015 Award Recipient

American College of Rheumatology Scientific Meeting

 Erlin A. Haacke, MD
University Medical Center Groningen (UMCG), The Netherlands

Abstract: Salivary Gland FcRL4+ B-Cells Are a Potential Source of Progenitor Cells for MALT Lymphoma in Primary Sjögren's Syndrome   Download Abstract
 

2014 Award Recipients

American College of Rheumatology Scientific Meeting

Maria B. Lauvsnes, MD
Stavanger University Hospital, Stavanger, Norway 


Abstract:
Hippocampal Atrophy Is Associated with Anti-NR2 Antibodies in Patients with Systemic Lupus Erythematosus and Primary Sjögren's Syndrome Download Abstract

Honorable Mention:
Jessica Tarn
Newcastle University, Newcastle Upon Tyne, United Kingdom


Abstract:
 Whole Blood microRNA Signature for Primary Sjögren’s Syndrome-Related Lymphoma  Download Abstract 

2013 Award Recipients

American College of Rheumatology Scientific Meeting

Gaétane Nocturne, MD
Paris-Sud University, Paris, France
The NKp30/B7H6 Axis Contributes to Pathogenesis in Primary Sjögren’s Syndrome
Abstract

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2012 Award Recipients

American College of Rheumatology Scientific Meeting

Hongen Yin, MD, PhD
NIH/NIDCR


Abstract:
Overexpression of BMP6 Is Associated with Loss of Salivary Gland Activity in Sjögren's Syndrome Patients and Mice Download Abstract

Honorable Mention:
Chang-Fu Kuo, MD
University of Nottingham


Abstract:
Sibling Relative Risk and Heritability of Sjögren’s Syndrome: A Nationwide Population Study in Taiwan Download Abstract

2011 Award Recipients

American College of Rheumatology Scientific Meeting


Joanne H. Reed, PhD

New York University School of Medicine
New York, New York 

Abstract: A Point Mutation in the SSA/Ro60 Autoantigen Which Prevents Y RNA Binding Attenuates a Requisite Signal for Cell Surface Expression and TLR-Dependent Inflammation Syndrome
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2010 Award Recipients

American College of Rheumatology Scientific Meeting

Kaleb M. Pauley, PhD
University of Florida, Gainesville
Gainesville , FL 

Abstract: Receptor-Mediated Small Interfering RNA Delivery in Sjogren's Syndrome '
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Honorable Mention:
Nienke Roescher, MD, MSc
Academic Medical Center-University of Amsterdam
The Netherlands

Abstract: Local TACI-lg Gene Therapy of the Salivary Gland of NOD Mice Reduces Auto-Immune Inflammation by Affecting the B Cell Compartment  Download Abstract

 

Honorable Mention:
Jacques-Olivier Pers, DDS, PhD
Brest University
Brest, France

Abstract:Δ4BAFF, an Alternate-Splice Isoform That Acts as a Transcription Factor To Enhance BAFF Production in Primary Sjögren's Syndrome    Download Abstract
 

Association for Research in Vision and Ophthalmology

Raheleh Rahimi Darabad, MD
Schepens Eye Research Institute
Harvard Medical School
Boston, Massachusetts

Abstract: Sex and Androgen Affects on Gene Expression in Autoimmune Lacrimal Glands
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2009 Award Recipients

American College of Rheumatology Scientific Meeting

Seshagiri Rao Nandula, PhD
University of Virginia
Charlottesville, Virginia

Abstract: Activation of Innate Immunity Leads to Accelerated Development of Sjogren's Syndrome-Like Disorder in NZB/W F1 Mice
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Association for Research in Vision and Ophthalmology

James Mun, PhD-candidate
School of Optometry,
University of California Berkeley

Abstract: Pre-exposure of Corneal Epithelial Cells to Human Tear Fluid Induces Protective Activity Against P. aeruginosa Virulence Mechanisms
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2008 Award Recipients

American College of Rheumatology Scientific Meeting

Angela Bikker, MSc
University Medical Center Utrecht
Utrecht, Netherlands

Abstract: Increased IL-7 expression correlates with immunopathology in exocrine glands of patients with SS and drives Th-1 associated immune responses 
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Honorable Mention:
Gunnel Nordmark, MD, PhD
Medical Sciences
Uppsala, Sweden
With colleagues from Malmö. Linköping, Stockholm, and Lund in Sweden and two institutes in Bergen, Norway

Abstract: Additive effects of major risk alleles of IRF6 and Stat 4 in primary Sjögren’s syndrome
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Association for Research in Vision and Ophthalmology

Shivaram Selvam, PhD-candidate
Ocular Surface Center, Doheny Eye Institute
University of Southern California Keck School of Medicine

Abstract: Impact of chronic stimulation with carbachol, histamine and serotonin on ion transport in a novel, chloride-secreting rabbit lacrimal acinar cell monolayer model
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2007 Award Recipients

American College of Rheumatology Scientific Meeting

Maria I. Christodoulou, BSc, PhD-Candidate and
Efstathia K. Kapsogeorgou, PhD
Department of Pathophysiology, School of Medicine,
National University of Athens,
Athens, Greece

Abstract: FOXP3+ T Regulatory Cells (Tregs) in the Autoimmune Lesions of Sjögren’s Syndrome (SS): Correlation with the Number of the Infiltrating Dendritic Cells and Macrophages
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Honorable Mention:
Marc Ittah, PhD
INSERM U802, Université Paris Sud, Rhumatologie Hopital de Bicêtre
Paris, France

Abstract: Reovirus-2 (a dsRNA Virus) and Poly (I:C) Induce High Expression of BAFF mRNA and Protein by Salivary Epithelial Cells Through TLR3 / Type 1-Interferon -Dependant and -Independent Pathways
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Honorable Mention:
Linn Strandberg, PhD, and Aurelie Ambrosi, MSc
Rheumatology Unit, Department of Medicine, Karolinska Institutet,
Stockholm, Sweden

Abstract: Interferon-Alpha Induces Up-Regulation and Nuclear Translocation of the Ro52 Autoantigen
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Association for Research in Vision and Ophthalmology

Shaohui Liu, MD, PhD
Schepens Eye Research Institute, Harvard Medical School

Abstract: Aromatase Influence on Gene Expression in the Meibomian Gland


2006 Award Recipients

American College of Rheumatology Scientific Meeting

Eshrat Emamian, DDS
University of Minnesota

Abstract: Comparison of Gene Expression Profiles Between Patients with Sjögren's Syndrome and Systemic Lupus Erythematosus
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Association for Research in Vision and Ophthalmology

Louis Tong, MBBS, FRCS, DM
Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine

Abstract: Transglutaminase-2 Mediates p65 Translocation from Cytoplasm to Nucleus in the UVB-activated NF-kappaB Pathway
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2005

American College of Rheumatology Scientific Meeting
Jacques-Eric Gottenberg, MD, PhD, France
Innate Immunity and Interferon Signaling Pathways: A Pivotal Pathogenic Role in Epithelial Cells of Salivary Glands and Ocular Surface in Primary Sjögren's Syndrome

Association for Research in Vision and Ophthalmology
Ashish K. Sharma , University of Virginia, Charlottesville, VA
Tumor Necrosis Factor-Induced Apoptosis in Corneal Epithelial Cells Is Attenuated by Novel Lacrimal Glycoprotein, Lacritin


2004

American College of Rheumatology Scientific Meeting
Biji Kurien, PhD, Oklahoma Research Medical Foundation (ORMF)
Adoptive Transfer of Lymphocytes from Mice with Sjögren’s-Like Syndrome Transfers Disease into Naïve Mice

Association for Research in Vision and Ophthalmology
Lihui Luo, MD, Baylor College of Medicine, Dallas, TX
Hyperosmolarity Induces Apoptosis through a cytochrome c-mediated death pathway and MAPK activation in human corneal epithelial cells


2003

American College of Rheumatology Scientific Meeting
Marc R. Kok, MD, National Institutes of Health, Bethesda, MD
"Local Adeno-Associated Virus Mediated IL-10 Gene Transfer has Disease Modifying Effects in a Murine Model of Sjögren's Syndrome"

Association for Research in Vision and Ophthalmology
Lihui Luo, MD, Baylor College of Medicine, Dallas, TX
"Experimental dry eye induces expression of inflammatory cytokines (IL-1Beta and TNF-Alpha), MMP-9 and activated MAPK by the corneal epithelium"


2002

American College of Rheumatology Scientific Meeting
Frédéric Lavie, MD, Bicetre Hospital, INSERM EMI 0109, Paris-Sud University, France
RANK and RANKL Expression in Salivary Glands from Patients with Primary Sjögren's Syndrome

Association for Research in Vision and Ophthalmology
Helline B. Paz MD, Harvard Medical School, Boston, MA
Mucin Packaging in the Conjunctival Goblet Cells of Vitamin D Receptor Ablated Mice


2001

American College of Rheumatology Scientific Meeting
Dr. Nicole Amft, University of Birmingham (United Kingdom)
Constitutive Chemokine and Chemokine Receptor Expression Contributes to the Pattern of Inflammatory Cell Infiltrates in Sjögren's Syndrome

Association for Research in Vision and Ophthalmology
Staci C. Walton, University of Virginia
Functional Analysis of Lacritin: Secretion Modulations, Cell Proliferation, Calcium Signaling, and Tyrosine Phosphorylation.


2000

Association for Research in Vision and Ophthalmology
Yoko Ogawa, MD, Keio University, Tokyo, Japan
Ultrastructural and immunohistochemic studies of lacrimal gland in patients with chronic graft-versus host disease


1999

Association for Research in Vision and Ophthalmology
Jennifer Cermak, PhD, Schepens Eye Research Institute, Boston, MA
The role of androgens in dry eye


1999

American College of Rheumatology Scientific Meeting
Sally Waterman, PhD, University of Adelaide, Adelaide, South Australia
Autoantibodies against muscarinic receptors in bot primary and secondary Sjögren's syndrome alter marine bladder contractility and are associated with autonomic symptoms


1998

Association for Research in Vision and Ophthalmology
Yolanda Diebold, PhD, Institute of Ophthalmology, Valladolid University, Valladolid, Spain
A confocal study of lectin binding sites in cultured conjunctival epithelium


1998

American College of Rheumatology Scientific Meeting
Maureen Rischmueller, MD, The Queens Elizabeth Hospital, South Australia
Salivary gland apoptosis in primary Sjögren's syndrome: A controlled study


1997

American College of Rheumatology Scientific Meeting
Mary Polihronis, PhD, National University of Athens, Athens, Greece
Modes of epithelial cell death and repair in Sjögren's syndrome


1996 Second International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance
Ikuko Toda, Schepens Eye Research Institute, Boston, MA
Gender and androgen-related impact on the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary glands of mouse models for Sjögren's syndrome

 


1996

American College of Rheumatology Scientific Meeting
Mariana J. Kaplan, MD, University of Michigan, Ann Arbor, MI
Is the liver a common extraglandular target in primary Sjögren's syndrome?


1996 Conference on Salivary Gland Biogenesis and Function
Thomas R. Esch, PhD
Autoantibodies in salivary hypofunction in the NOD mouse

 


1995

American College of Rheumatology Scientific Meeting
Douglas A. Jabs, MD, Johns Hopkins University, Baltimore, MD
Immunopathogenesis of lacrimal gland inflammation in MRL/Mplprllpr mice