The Foundation recognizes excellence in research by new and/or young investigators who present outstanding abstracts on Sjögren’s syndrome research at professional meetings.The SSF Outstanding Abstract Award is designed to reward exceptional research efforts and encourage investigators to continue their focus on Sjögren’s syndrome throughout their career. 2010 Award Recipients American College of Rheumatology Scientific Meeting
To Be Announced Association for Research in Vision and Ophthalmology Raheleh Rahimi Darabad, MD Schepens Eye Research Institute Harvard Medical School Boston, Massachusetts
Abstract: Sex and Androgen Affects on Gene Expression in Autoimmune Lacrimal Glands Download Abstract
2009 Award Recipients American College of Rheumatology Scientific Meeting
Seshagiri Rao Nandula, PhD University of Virginia Charlottesville, Virginia Abstract: Activation of Innate Immunity Leads to Accelerated Development of Sjogren's Syndrome-Like Disorder in NZB/W F1 Mice Download Abstract
Association for Research in Vision and Ophthalmology James Mun, PhD-candidate School of Optometry, University of California Berkeley
Abstract: Pre-exposure of Corneal Epithelial Cells to Human Tear Fluid Induces Protective Activity Against P. aeruginosa Virulence Mechanisms Download Abstract
2008 Award RecipientsAmerican College of Rheumatology Scientific Meeting Angela Bikker, MSc University Medical Center Utrecht Utrecht, Netherlands
Abstract: Increased IL-7 expression correlates with immunopathology in exocrine glands of patients with SS and drives Th-1 associated immune responses Download Abstract
Honorable Mention: Gunnel Nordmark, MD, PhD Medical Sciences Uppsala, Sweden With colleagues from Malmö. Linköping, Stockholm, and Lund in Sweden and two institutes in Bergen, Norway
Abstract: Additive effects of major risk alleles of IRF6 and Stat 4 in primary Sjögren’s syndrome Download Abstract
Association for Research in Vision and Ophthalmology
Shivaram Selvam, PhD-candidate Ocular Surface Center, Doheny Eye Institute University of Southern California Keck School of Medicine
Abstract: Impact of chronic stimulation with carbachol, histamine and serotonin on ion transport in a novel, chloride-secreting rabbit lacrimal acinar cell monolayer model Download Abstract
2007 Award Recipients
American College of Rheumatology Scientific Meeting Maria I. Christodoulou, BSc, PhD-Candidate and Efstathia K. Kapsogeorgou, PhD Department of Pathophysiology, School of Medicine, National University of Athens, Athens, Greece
Abstract: FOXP3+ T Regulatory Cells (Tregs) in the Autoimmune Lesions of Sjögren’s Syndrome (SS): Correlation with the Number of the Infiltrating Dendritic Cells and Macrophages Download Abstract
Honorable Mention: Marc Ittah, PhD INSERM U802, Université Paris Sud, Rhumatologie Hopital de Bicêtre Paris, France
Abstract: Reovirus-2 (a dsRNA Virus) and Poly (I:C) Induce High Expression of BAFF mRNA and Protein by Salivary Epithelial Cells Through TLR3 / Type 1-Interferon -Dependant and -Independent Pathways Download Abstract
Honorable Mention: Linn Strandberg, PhD, and Aurelie Ambrosi, MSc Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Abstract: Interferon-Alpha Induces Up-Regulation and Nuclear Translocation of the Ro52 Autoantigen Download Abstract Association for Research in Vision and Ophthalmology Shaohui Liu, MD, PhD Schepens Eye Research Institute, Harvard Medical School
Abstract: Aromatase Influence on Gene Expression in the Meibomian Gland 2006 Award Recipients
American College of Rheumatology Scientific Meeting Eshrat Emamian, DDS University of Minnesota
Abstract: Comparison of Gene Expression Profiles Between Patients with Sjögren's Syndrome and Systemic Lupus Erythematosus Download Abstract Association for Research in Vision and Ophthalmology Louis Tong, MBBS, FRCS, DM Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine
Abstract: Transglutaminase-2 Mediates p65 Translocation from Cytoplasm to Nucleus in the UVB-activated NF-kappaB Pathway Download Abstract
| | 2005 | American College of Rheumatology Scientific Meeting Jacques-Eric Gottenberg, MD, PhD, France Innate Immunity and Interferon Signaling Pathways: A Pivotal Pathogenic Role in Epithelial Cells of Salivary Glands and Ocular Surface in Primary Sjögren's Syndrome Association for Research in Vision and Ophthalmology Ashish K. Sharma , University of Virginia, Charlottesville, VA Tumor Necrosis Factor-Induced Apoptosis in Corneal Epithelial Cells Is Attenuated by Novel Lacrimal Glycoprotein, Lacritin |
| | 2004 | American College of Rheumatology Scientific Meeting Biji Kurien, PhD, Oklahoma Research Medical Foundation (ORMF) Adoptive Transfer of Lymphocytes from Mice with Sjögren’s-Like Syndrome Transfers Disease into Naïve Mice Association for Research in Vision and Ophthalmology Lihui Luo, MD, Baylor College of Medicine, Dallas, TX Hyperosmolarity Induces Apoptosis through a cytochrome c-mediated death pathway and MAPK activation in human corneal epithelial cells |
| 2003
| American College of Rheumatology Scientific Meeting Marc R. Kok, MD, National Institutes of Health, Bethesda, MD "Local Adeno-Associated Virus Mediated IL-10 Gene Transfer has Disease Modifying Effects in a Murine Model of Sjögren's Syndrome" Association for Research in Vision and Ophthalmology Lihui Luo, MD, Baylor College of Medicine, Dallas, TX "Experimental dry eye induces expression of inflammatory cytokines (IL-1Beta and TNF-Alpha), MMP-9 and activated MAPK by the corneal epithelium" |
| | 2002 | American College of Rheumatology Scientific Meeting Frédéric Lavie, MD, Bicetre Hospital, INSERM EMI 0109, Paris-Sud University, France RANK and RANKL Expression in Salivary Glands from Patients with Primary Sjögren's Syndrome Association for Research in Vision and Ophthalmology Helline B. Paz MD, Harvard Medical School, Boston, MA Mucin Packaging in the Conjunctival Goblet Cells of Vitamin D Receptor Ablated Mice |
| | 2001 | American College of Rheumatology Scientific Meeting Dr. Nicole Amft, University of Birmingham (United Kingdom) Constitutive Chemokine and Chemokine Receptor Expression Contributes to the Pattern of Inflammatory Cell Infiltrates in Sjögren's Syndrome Association for Research in Vision and Ophthalmology Staci C. Walton, University of Virginia Functional Analysis of Lacritin: Secretion Modulations, Cell Proliferation, Calcium Signaling, and Tyrosine Phosphorylation. |
| | 2000 | Association for Research in Vision and Ophthalmology Yoko Ogawa, MD, Keio University, Tokyo, Japan Ultrastructural and immunohistochemic studies of lacrimal gland in patients with chronic graft-versus host disease |
| | 1999 | Association for Research in Vision and Ophthalmology Jennifer Cermak, PhD, Schepens Eye Research Institute, Boston, MA The role of androgens in dry eye |
| | 1999 | American College of Rheumatology Scientific Meeting Sally Waterman, PhD, University of Adelaide, Adelaide, South Australia Autoantibodies against muscarinic receptors in bot primary and secondary Sjögren's syndrome alter marine bladder contractility and are associated with autonomic symptoms |
| | 1998 | Association for Research in Vision and Ophthalmology Yolanda Diebold, PhD, Institute of Ophthalmology, Valladolid University, Valladolid, Spain A confocal study of lectin binding sites in cultured conjunctival epithelium |
| | 1998 | American College of Rheumatology Scientific Meeting Maureen Rischmueller, MD, The Queens Elizabeth Hospital, South Australia Salivary gland apoptosis in primary Sjögren's syndrome: A controlled study |
| | 1997 | American College of Rheumatology Scientific Meeting Mary Polihronis, PhD, National University of Athens, Athens, Greece Modes of epithelial cell death and repair in Sjögren's syndrome |
| | 1996 | Second International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance Ikuko Toda, Schepens Eye Research Institute, Boston, MA Gender and androgen-related impact on the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary glands of mouse models for Sjögren's syndrome |
| | 1996 | American College of Rheumatology Scientific Meeting Mariana J. Kaplan, MD, University of Michigan, Ann Arbor, MI Is the liver a common extraglandular target in primary Sjögren's syndrome? |
| | 1996 | Conference on Salivary Gland Biogenesis and Function Thomas R. Esch, PhD Autoantibodies in salivary hypofunction in the NOD mouse |
| | 1995 | American College of Rheumatology Scientific Meeting Douglas A. Jabs, MD, Johns Hopkins University, Baltimore, MD Immunopathogenesis of lacrimal gland inflammation in MRL/Mplprllpr mice |
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