The Foundation recognizes excellence in research by new and/or young investigators who present outstanding abstracts on Sjögren’s syndrome research at professional meetings.The SSF Outstanding Abstract Award is designed to reward exceptional research efforts and encourage investigators to continue their focus on Sjögren’s syndrome throughout their career. 2009 Award Recipients American College of Rheumatology Scientific Meeting
Seshagiri Rao Nandula, PhD
University of Virginia
Charlottesville, Virginia Abstract: Activation of Innate Immunity Leads to Accelerated Development of Sjogren's Syndrome-Like Disorder in NZB/W F1 Mice
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Association for Research in Vision and Ophthalmology James Mun, PhD-candidate
School of Optometry,
University of California Berkeley
Abstract: Pre-exposure of Corneal Epithelial Cells to Human Tear Fluid Induces Protective Activity Against P. aeruginosa Virulence Mechanisms
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2008 Award RecipientsAmerican College of Rheumatology Scientific Meeting Angela Bikker, MSc
University Medical Center Utrecht
Utrecht, Netherlands
Abstract: Increased IL-7 expression correlates with immunopathology in exocrine glands of patients with SS and drives Th-1 associated immune responses
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Honorable Mention:
Gunnel Nordmark, MD, PhD
Medical Sciences
Uppsala, Sweden
With colleagues from Malmö. Linköping, Stockholm, and Lund in Sweden and two institutes in Bergen, Norway
Abstract: Additive effects of major risk alleles of IRF6 and Stat 4 in primary Sjögren’s syndrome
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Association for Research in Vision and Ophthalmology
Shivaram Selvam, PhD-candidate
Ocular Surface Center, Doheny Eye Institute
University of Southern California Keck School of Medicine
Abstract: Impact of chronic stimulation with carbachol, histamine and serotonin on ion transport in a novel, chloride-secreting rabbit lacrimal acinar cell monolayer model
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2007 Award Recipients
American College of Rheumatology Scientific Meeting
Maria I. Christodoulou, BSc, PhD-Candidate and
Efstathia K. Kapsogeorgou, PhD
Department of Pathophysiology, School of Medicine,
National University of Athens,
Athens, Greece
Abstract: FOXP3+ T Regulatory Cells (Tregs) in the Autoimmune Lesions of Sjögren’s Syndrome (SS): Correlation with the Number of the Infiltrating Dendritic Cells and Macrophages
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Honorable Mention:
Marc Ittah, PhD
INSERM U802, Université Paris Sud, Rhumatologie Hopital de Bicêtre
Paris, France
Abstract: Reovirus-2 (a dsRNA Virus) and Poly (I:C) Induce High Expression of BAFF mRNA and Protein by Salivary Epithelial Cells Through TLR3 / Type 1-Interferon -Dependant and -Independent Pathways
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Honorable Mention:
Linn Strandberg, PhD, and Aurelie Ambrosi, MSc
Rheumatology Unit, Department of Medicine, Karolinska Institutet,
Stockholm, Sweden
Abstract: Interferon-Alpha Induces Up-Regulation and Nuclear Translocation of the Ro52 Autoantigen
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Association for Research in Vision and Ophthalmology Shaohui Liu, MD, PhD
Schepens Eye Research Institute, Harvard Medical School
Abstract: Aromatase Influence on Gene Expression in the Meibomian Gland
2006 Award Recipients
American College of Rheumatology Scientific Meeting
Eshrat Emamian, DDS
University of Minnesota
Abstract: Comparison of Gene Expression Profiles Between Patients with Sjögren's Syndrome and Systemic Lupus Erythematosus
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Louis Tong, MBBS, FRCS, DM
Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine
Abstract: Transglutaminase-2 Mediates p65 Translocation from Cytoplasm to Nucleus in the UVB-activated NF-kappaB Pathway
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| | 2005 | American College of Rheumatology Scientific Meeting
Jacques-Eric Gottenberg, MD, PhD, France
Innate Immunity and Interferon Signaling Pathways: A Pivotal Pathogenic Role in Epithelial Cells of Salivary Glands and Ocular Surface in Primary Sjögren's Syndrome Association for Research in Vision and Ophthalmology
Ashish K. Sharma , University of Virginia, Charlottesville, VA
Tumor Necrosis Factor-Induced Apoptosis in Corneal Epithelial Cells Is Attenuated by Novel Lacrimal Glycoprotein, Lacritin |
| | 2004 | American College of Rheumatology Scientific Meeting
Biji Kurien, PhD, Oklahoma Research Medical Foundation (ORMF)
Adoptive Transfer of Lymphocytes from Mice with Sjögren’s-Like Syndrome Transfers Disease into Naïve Mice Association for Research in Vision and Ophthalmology
Lihui Luo, MD, Baylor College of Medicine, Dallas, TX
Hyperosmolarity Induces Apoptosis through a cytochrome c-mediated death pathway and MAPK activation in human corneal epithelial cells |
| 2003
| American College of Rheumatology Scientific Meeting
Marc R. Kok, MD, National Institutes of Health, Bethesda, MD
"Local Adeno-Associated Virus Mediated IL-10 Gene Transfer has Disease Modifying Effects in a Murine Model of Sjögren's Syndrome" Association for Research in Vision and Ophthalmology
Lihui Luo, MD, Baylor College of Medicine, Dallas, TX
"Experimental dry eye induces expression of inflammatory cytokines (IL-1Beta and TNF-Alpha), MMP-9 and activated MAPK by the corneal epithelium" |
| | 2002 | American College of Rheumatology Scientific Meeting
Frédéric Lavie, MD, Bicetre Hospital, INSERM EMI 0109, Paris-Sud University, France
RANK and RANKL Expression in Salivary Glands from Patients with Primary Sjögren's Syndrome Association for Research in Vision and Ophthalmology
Helline B. Paz MD, Harvard Medical School, Boston, MA
Mucin Packaging in the Conjunctival Goblet Cells of Vitamin D Receptor Ablated Mice |
| | 2001 | American College of Rheumatology Scientific Meeting
Dr. Nicole Amft, University of Birmingham (United Kingdom)
Constitutive Chemokine and Chemokine Receptor Expression Contributes to the Pattern of Inflammatory Cell Infiltrates in Sjögren's Syndrome Association for Research in Vision and Ophthalmology
Staci C. Walton, University of Virginia
Functional Analysis of Lacritin: Secretion Modulations, Cell Proliferation, Calcium Signaling, and Tyrosine Phosphorylation. |
| | 2000 | Association for Research in Vision and Ophthalmology
Yoko Ogawa, MD, Keio University, Tokyo, Japan
Ultrastructural and immunohistochemic studies of lacrimal gland in patients with chronic graft-versus host disease |
| | 1999 | Association for Research in Vision and Ophthalmology
Jennifer Cermak, PhD, Schepens Eye Research Institute, Boston, MA
The role of androgens in dry eye |
| | 1999 | American College of Rheumatology Scientific Meeting
Sally Waterman, PhD, University of Adelaide, Adelaide, South Australia
Autoantibodies against muscarinic receptors in bot primary and secondary Sjögren's syndrome alter marine bladder contractility and are associated with autonomic symptoms |
| | 1998 | Association for Research in Vision and Ophthalmology
Yolanda Diebold, PhD, Institute of Ophthalmology, Valladolid University, Valladolid, Spain
A confocal study of lectin binding sites in cultured conjunctival epithelium |
| | 1998 | American College of Rheumatology Scientific Meeting
Maureen Rischmueller, MD, The Queens Elizabeth Hospital, South Australia
Salivary gland apoptosis in primary Sjögren's syndrome: A controlled study |
| | 1997 | American College of Rheumatology Scientific Meeting
Mary Polihronis, PhD, National University of Athens, Athens, Greece
Modes of epithelial cell death and repair in Sjögren's syndrome |
| | 1996 | Second International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance
Ikuko Toda, Schepens Eye Research Institute, Boston, MA
Gender and androgen-related impact on the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary glands of mouse models for Sjögren's syndrome |
| | 1996 | American College of Rheumatology Scientific Meeting
Mariana J. Kaplan, MD, University of Michigan, Ann Arbor, MI
Is the liver a common extraglandular target in primary Sjögren's syndrome? |
| | 1996 | Conference on Salivary Gland Biogenesis and Function
Thomas R. Esch, PhD
Autoantibodies in salivary hypofunction in the NOD mouse |
| | 1995 | American College of Rheumatology Scientific Meeting
Douglas A. Jabs, MD, Johns Hopkins University, Baltimore, MD
Immunopathogenesis of lacrimal gland inflammation in MRL/Mplprllpr mice |
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