Results of a comparative cohort study between COVID-19 patients (n=104) and rheumatic disease patients with COVID-19 (n=52) found that the group with rheumatic disease was more likely to need mechanical ventilation (48% vs 18%; multivariable OR = 3.11 (95% CI 1.07 to 9.05), though similar clinical features and hospitalization rates were observed (44% vs 40%; p=0.50). Notably, the mortality rate between the two groups in this study were similar, with rheumatic disease patients at 6% and non-rheumatic disease COVID-19 patients at 4% (p=0.69). The authors note that while these findings have important implications for patients with rheumatic disease, further validation is required. Additionally, 75% of the rheumatic dis- ease patients included in this study were on immunosuppressive medications. Patients were identified from a U.S. healthcare system between March 1, 2020, and April 8, 2020.
D’Silva KM, Serling-Boyd N, Wallwork R, et al. Clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) and rheumatic disease: a comparative cohort study from a US ‘hot spot’. Annals of the Rheumatic Diseases Published Online First: 26 May 2020. doi: 10.1136/annrheumdis-2020-217888